Momen, ASarker, C BSiddiqui, N IHuq, M HJamal, M FTalukder, S IRahman, K M2003-07-022009-05-272003-07-022009-05-272003-07-02Momen A, Sarker CB, Siddiqui NI, Huq MH, Jamal MF, Talukder SI, Rahman KM. Hairy cell leukaemia with advanced treatment - a case report. Mymensingh Medical Journal. 2003 Jul; 12(2): 134-7http://imsear.searo.who.int/handle/123456789/1224Mymensingh Medical Journal.A case of hairy cell leukaemia (HCL), a rare leukaemia, is reported here. The patient was presented with high grade continuous fever with left upper abdominal discomfort for 6 days. He was moderately anaemic, had no peripheral lymphadenopathy with mild hepatosplenomegaly. He was anaemic (Hb-7.8 gm/dl), total leukocyte count was 20 x 109/L. Peripheral blood film showed lymphocytosis (92%) with neutropenia (8%) and absolute neutophil count (ANC) was 1 x 109/L. On review, 88% of the peripheral cells had peripheral hairy projections resembling hairy cell (HC). Bone marrow examination was consistent with HCL (morrow hairy cell = 52%) including marker studies. Tartrate resistant acid phosphatase test (TRAP) was also positive. He had opportunistic mycobecterial infection giving a positive bronchial lavage for acid fast bacilli. After controlling the infection he was advised a single dose chemotherapy of 2-chlorodeoxyadenosine (2-CDA). After that he was in partial remission and after 25 months clinical and pathological relapses occurred and a second dose of 2-CDA was given and the patient went into complete remission.engAdultAntineoplastic Agents --therapeutic useAntitubercular Agents --therapeutic useBone Marrow ExaminationCladribine --therapeutic useHumansLeukemia, Hairy Cell --complicationsMaleMycobacterium Infections --complicationsRemission InductionTreatment OutcomeCase Reports