Singh, NShukla, M MAsthana, O PSharma, V P2009-05-272009-05-271998-06-14Singh N, Shukla MM, Asthana OP, Sharma VP. Effectiveness of alpha-beta arteether in clearing Plasmodium falciparum parasitemia in central India (Madhya Pradesh). The Southeast Asian Journal of Tropical Medicine and Public Health. 1998 Jun; 29(2): 225-7http://imsear.searo.who.int/handle/123456789/32786The Southeast Asian Journal of Tropical Medicine and Public Health.Forty-six patients (25 Females + 21 Males) of uncomplicated Plasmodium falciparum in districts Jabalpur and Mandla of central India (Madhya Pradesh) were administered alpha-beta arteether (an ethyl derivative of qinghaosu), intramuscularly for 3 consecutive days (150 mg once a day). The results revealed that there was rapid control of fever in all the patients without administration of any antipyretic drug. The mean parasite clearance time was 30.78 +/- 10.92 hours and recrudescence/reinfection rate was 6.7% within 28 days. Study indicates that arteether, besides being a potent and fast acting schizontocidal drug, also exhibited gametocytocidal action on P. falciparum.engAdolescentAdultAnimalsAntimalarials --pharmacologyArtemisininsFemaleHumansIndiaMalaria, Falciparum --drug therapyMaleMiddle AgedParasitemia --drug therapyPlasmodium falciparum --drug effectsSesquiterpenes --pharmacologyClinical Trial