A V, Raveendran2020-04-102020-04-102018-04A V Raveendran. Acute febrile illness: A stepwise approach for clinicians. Indian Journal of Medical Sciences. 2018 APR; 70(2): 30-370019-53591998-3654http://imsear.searo.who.int/handle/123456789/196494Acute febrile illness (AFI) is a common clinical problem, and can be due to various causes. AFI without localizing featuresacute undifferentiated febrile illness is a diagnostic challenge. Knowledge about common infections present in that particular area will give a clue to the probable etiology. But because of variety of causes and atypical presentations diagnosis of AFI remains to be a great challenge. In this review we are describing a stepwise approach for the diagnosis and management of AFI which will be useful for the practicing cliniciansacute febrile illnessacute undifferentiated febrile illnessnon-malarial acute febrile illnesshost biomarkerstravellersJournal ArticleIndiaDepartment of Orthopaedics, Badr Al Samaa, Barka, Sultanate of Oman.