Davis, S VShenoi, S DBalachandran, CPai, S B2002-04-242009-05-282002-04-242009-05-282002-04-24Davis SV, Shenoi SD, Balachandran C, Pai SB. A fatal case of erythema necroticans. Indian Journal of Leprosy. 2002 Apr-Jun; 74(2): 145-9http://imsear.searo.who.int/handle/123456789/55139Erythema nodosum leprosum (ENL) classically presents as tender, erythematous nodules over the face, arms and legs. Severe ENL can become vesicular or bullous and break-down and is termed erythema necroticans (Jopling & McDougall, 1996) and is treated with corticosteroids. The causes of death in a majority of leprosy patients are the same as in the general population, with the exception of renal damage in lepromatous leprosy. There is possible increased mortality from side-effects of antileprosy drugs, steroids, or other drugs used in reactions, from toxaemia in severe reactions, and from asphyxia due to glottic oedema (Jopling & McDougall, 1996). We report here a case of erythema necroticans, the cause of death being septicaemia, secondary to skin ulcers and urinary tract infection, precipitated by corticosteroids.engAdrenal Cortex Hormones --adverse effectsAnti-Infective Agents --therapeutic useCiprofloxacin --therapeutic useErythema Nodosum --drug therapyFatal OutcomeHumansLeprosy, Lepromatous --drug therapyMaleMiddle AgedSkin Diseases, Vesiculobullous --drug therapyCase Reports