Peettakkandy, VijayanSoren, Subrat KumarK.K., VineethCholakkal, Shanavas2020-09-242020-09-242020-04Peettakkandy Vijayan, Soren Subrat Kumar, K.K. Vineeth, Cholakkal Shanavas. Landouzy Sepsis (Atypical ARDS like Features) and Paradoxical Reaction of Tubercular Meningitis Complications, in a Case of Disseminated Extrapulmonary Tuberculosis. International Journal of Contemporary Medical Research . 2020 Apr; 7(4): d1-d52393-915X2454-7379http://imsear.searo.who.int/handle/123456789/202893Introduction: Chronic Obstructive Pulmonary Disease(COPD) is a major health problem globally. Spirometry is theGold standard for the diagnosis of COPD and it also gradesit’s severity. 6MWT is a simple reproducible test to assess thepatient’s functional capacity. It is of help in management andprediction of prognosis. Objective: This study was done to findcorrelation between 6MWT results with patient’s clinical andspirometric parameters. The study also assessed if 6 minutewalk distance (6MWD) can be an alternative to spirometry inpredicting severity of COPD in resource poor setup.Material and methods: This was a hospital based crosssectional study. 60 consecutive confirmed patients of COPD(by GOLD guidelines) were included in the study afterapplying inclusion and exclusion criteria. Severity wasassessed by pre and post-bronchodilator spirometry test. Thiswas followed by 6MWT as per ATS guidelines. 6MWD wasrecorded and % predicted 6MWD was also calculated. Resultsof 6MWT were correlated with spirometric and clinicalparameters of the patients.Results: 6MWD had statistically significant (p <.05) positivecorrelation with following parameters: Height, FEV1, %predicted FEV1, FVC, FEV1/FVC and PEFR. Correlationwith age, weight and BMI was not significant. % 6MWDsignificantly correlated with Height, FEV1, % predictedFEV1, FVC and PEFR. Distances in meters walked bydifferent severity groups were as follows: Mild: 410 + 15;Moderate: 367.66 + 57.71; Severe: 364.60 + 62.91 and Verysevere: 281.21 + 55.99. On one way analysis of variance(ANOVA) these differences were found significant (p <.01)Conclusion: In this study 6MWD and percent 6MWD hadsignificant positive correlation with patients’ parameters(Height, FEV1, %FEV1, FVC and PEFR). The severity ofCOPD may be assessed with 6MWT.Disseminated TBParadoxical ReactionsARDSTubercular Meningitis.Journal ArticleIndiaAssociate Professor, Department of Neurosurgery, Government. Medical College, Kozhikode, KeralaSenior Resident, Department of Neurosurgery, Government Medical College, Kozhikode, KeralaMch Trainee, Department of Neurosurgery, Government Medical College, Kozhikode, KeralaMch Trainee, Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India