Das, C PPrabhakar, SLal, VKharbanda, P S2002-12-112009-06-032002-12-112009-06-032002-12-11Das CP, Prabhakar S, Lal V, Kharbanda PS. Scleroderma, stroke, optic neuropathy: a rare association. Neurology India. 2002 Dec; 50(4): 504-7http://imsear.searo.who.int/handle/123456789/12140118 references.A known case of scleroderma presented with right hemiparesis, focal seizures, optic atrophy and gangrene of digits. There was no evidence of peripheral nerve or muscle involvement. MRI showed multifocal infarcts in both cerebral hemispheres. MR angiography revealed poor flow in bilateral carotid arteries with collateralization from posterior circulation. She improved with phenytoin, nifedipine, antibiotics and immunosuppressants. The rarity of central nervous system affliction in scleroderma and large vessel vasculitis is discussed along with review of literature.engAdultFemaleHumansOptic Atrophy --etiologyScleroderma, Systemic --complicationsStroke --etiologyCase Reports