Sethi, Neha KChadha, CharuBajaj, ManpreetMoond, Harshita2023-08-252023-08-252022-12Sethi Neha K, Chadha Charu, Bajaj Manpreet, Moond Harshita. Central retinal vein occlusion as primary ocular manifestation of rhino-orbital-cerebral mucormycosis: A case report. Indian Journal of Ophthalmology. 2022 Dec; 70(12): 4451-44531998-36890301-4738http://imsear.searo.who.int/handle/123456789/224766Mucormycosis is a serious, rapidly progressing, life-threatening, and sight threatening fungal infection frequently seen in diabetics and immunocompromised patients. We report a rare occurrence of rhino-orbital mucormycosis presenting as unilateral central retinal vein occlusion (CRVO) and no other ocular signs of infection in a 65-year-old diabetic male. The definitive diagnosis was made by nasal biopsy which confirmed broad branching aseptate fungal hyphae. The patient was treated with amphotericin B for mucormycosis and intravitreal anti-vascular growth factor (anti-VEGF) drug for macular edema. To conclude, although ophthalmoplegia is the most common ocular presentation and retinal artery occlusion is the most common cause of visual loss in mucormycosis, it may have many varied presentations including CRVO. A high index of suspicion must be kept in diabetics and immunocompromised patientsCentral retinal vein occlusiondiabetes mellitusmacular edemaamphotericin Brhino?orbital?cerebral mucormycosisRhizopusJournal ArticleIndiaDepartment of Ophthalmology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India