Cancino, J. A. D.Álvarez, C. J. S.Ramírez, K. A. Z.2024-09-242024-09-242023-10Cancino J. A. D., Álvarez C. J. S., Ramírez K. A. Z.. Use of liraglutide in the patient with obesity and type 2 diabetes mellitus: a literature review. International Journal of Basic & Clinical Pharmacology. 2023 Sept; 12(5): 755-7582319-20032279-0780https://imsear.searo.who.int/handle/123456789/226579Obesity and type 2 diabetes mellitus represent two of the most pressing public health challenges globally. In recent decades, an alarming increase in the prevalence of both conditions has been observed, which has led to a significant increase in the burden of disease and an increased search for effective therapeutic strategies. As evidence accumulates on the efficacy and safety of Liraglutide in this patient population, a comprehensive review of the available scientific literature is necessary. The objective of this literature review is to analyze and synthesize relevant studies investigating the use of liraglutide in patients with obesity and type 2 diabetes mellitus, in order to provide a comprehensive view on its effectiveness, indications, complications and management. In conclusion, the use of liraglutide in patients with obesity and type 2 diabetes mellitus has been shown to be an effective therapeutic option to improve glycemic control, promote weight loss and reduce cardiovascular risk. This drug, as a GLP-1 receptor agonist, stimulates insulin secretion, suppresses excessive glucagon release and delays gastric emptying, which contributes to the improvement in glycemic control.LiraglutideDiabetes mellitusGLP-1 receptorJournal ArticleIndiaDepartamento De Medicina Interna, Instituto Mexicano Del Seguro Social, Jesús María, Aguascalientes, MexicoDepartamento De Medicina Interna, Instituto Mexicano Del Seguro Social, Jesús María, Aguascalientes, MexicoDepartamento De medicina interna, Instituto Mexicano del Seguro Social, Mérida, Yucatán, Mexico