Cook, WHMcKelvie, JWallace, HBMisra, SL2020-04-102020-04-102019-07Cook WH, McKelvie J, Wallace HB, Misra SL. Comparison of higher order wavefront aberrations with four aberrometers. Indian Journal of Ophthalmology. 2019 Jul; 67(7): 1030-10350301-47381998-3689http://imsear.searo.who.int/handle/123456789/197328Purpose: To evaluate the agreement of selected higher order aberration measurements between aberrometers based on three different wavefront technologies. Methods: Twenty-three eyes of 23 participants were compared between Zywave, OPD-Scan III, and iDesign aberrometers, for total ocular aberrations. Participants were between 19 and 69 years of age, and exclusion criteria were previous ocular surgery or trauma, contact lens wear within the preceding 2 weeks, and ocular or systemic disease. Corneal aberrations were compared between the OPD-Scan III and GALILEI™ G2 aberrometers. Zernike coefficients of vertical and oblique trefoil, vertical and horizontal coma, and spherical aberration were analyzed in R software. Results: In all, 276 scans were captured in total, with a male-to-female ratio of 11:12. Total ocular vertical coma [mean difference (MD) = 0.026 ?m, P < 0.005], vertical trefoil (MD = 0.033 ?m, P < 0.05), and spherical aberration (MD = 0.022 ?m, P < 0.05) differed significantly between the iDesign and OPD-Scan III. Differences in total vertical (MD = 0.072 ?m, P < 0.05) and oblique trefoil (MD = 0.058 ?m, P < 0.05) were demonstrated between the Zywave and OPD-Scan III, and spherical aberration (MD = 0.030 ?m, P < 0.005) between iDesign and Zywave. iDesign corneal horizontal coma (MD = 0.025 ?m, P < 0.05) and spherical aberration (MD = 0.043 ?m, P < 0.005) measurements were significantly different between the GALILEI™ G2 and the OPD-Scan III. Conclusion: Zywave, iDesign, and OPD-Scan III, and GALILEITM G2 and OPD-Scan III may be used interchangeably for their total ocular and corneal wavefront functions, respectively; however, care must be taken if using these devices for guiding ablation or monitoring corneal disease.Higher order aberrationsLASIKwavefront aberrometryJournal ArticleIndiaDepartment of Ophthalmology and New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand