Bhagyalakshmi, ASreelekha, ASridevi, SChandralekha, JParvathi, GVenkatalakshmi, A2014-05-072014-05-072014-04Bhagyalakshmi A, Sreelekha A, Sridevi S, Chandralekha J, Parvathi G, Venkatalakshmi A. Prospective study of histopathological patterns of ovarian tumours in a tertiary care centre. International Journal of Research in Medical Sciences. 2014 Apr-Jun; 2(2): 448-456.http://imsear.searo.who.int/handle/123456789/150654Background: Ovarian tumours account for 3% of all cancers amongst women, being the second most common cancer of the female genital tract. The ovarian tumours are highly heterogenous with a wide range of histological patterns. Aim of current study was to study the histological patterns and the age incidence of the ovarian tumours in our institute. Methods: The present study is a prospective study conducted in the department of pathology, Andhra Medical College, from August 2011 to July 2013. Results: We received a total of 267 specimens of ovarian tumours during this period, out of which, 263 were primary and 4 were secondary tumours. Benign tumours were 209 (78.3%), borderline were 10 (3.7%) and malignant were 48 (18%) in numbers. Overall surface epithelial tumours constituted the majority of tumours accounting for 214 (80.2%) cases, followed by germ cell tumours 38 (14.2%) and sexcord stromal tumours 11 (4.1%). The single most common tumour diagnosed was serous cystadenoma. The most common malignant tumour was serous cystadenocarcinoma. The age groups affected ranged from 11-70 years. The peak age incidences for different histological types were as follows: surface epithelial tumours: 21-50 years, germ cell tumours: 21-30 years, sexcord stromal tumours: 51-60years. Benign tumours were more common in 21-40 years of age, borderline in 31-50 years and malignant tumours in 41-50 years age group. Conclusion: The results from our study were comparable with those reported in literature; however malignant serous and mucinous tumours showed a lower peak age incidence in our study. Krukenberg tumours also occurred in younger age group in our study.enOvarian tumoursHistopathological patternsAge groupsProspective study of histopathological patterns of ovarian tumours in a tertiary care centre.Article