Unalp, H RKamer, EDerici, HAtahan, KBalci, UDemirdoven, CNazli, OOnal, M A2008-04-162009-06-022008-04-162009-06-022008-04-16Unalp HR, Kamer E, Derici H, Atahan K, Balci U, Demirdoven C, Nazli O, Onal MA. Fournier's gangrene: evaluation of 68 patients and analysis of prognostic variables. Journal of Postgraduate Medicine. 2008 Apr-Jun; 54(2): 102-5http://imsear.searo.who.int/handle/123456789/116255CONTEXT: Fournier's gangrene (FG) is a rapidly progressing acute gangrenous infection of the anorectal and urogenital area. AIMS: The objectives of this study were to investigate patients with FG and to determine risk factors that affect mortality. SETTINGS AND DESIGN: Retrospective clinical study. MATERIALS AND METHODS: Clinical presentations and outcomes of surgical treatments were evaluated in 68 patients with FG. Statistical Analysis Used: Chi-square, Student's t -test, and logistic regression test. RESULTS: Mean age of patients was 54 and female-to-male ratio was 9:59. Among the predisposing factors, diabetes mellitus (DM) was the most common ( n =24, 35.3%), and sepsis on admission was detected in 31 (45.6%) and 15 (22.1%) patients, respectively. Seven (10.3%) patients died. Using logistic regression test, Fournier's Gangrene Severity Index (FGSI)> 9, DM and sepsis on admission were found as prognostic factors. CONCLUSIONS: FG has a high mortality rate, especially in patients with DM and sepsis. An FGSI value> 9 indicates high mortality rate.engAdultAgedAged, 80 and overFemaleFournier Gangrene --complicationsHumansLength of StayLogistic ModelsMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk FactorsSepsis --complicationsSeverity of Illness IndexTime FactorsTreatment OutcomeJournal Article