Bharadwaj, RagyaQuadros, ShawonFaruqi, Nafis AhmadPinto, Maria Jose WisemanRodrigues, Savio2019-12-062019-12-062018-03Bharadwaj Ragya, Quadros Shawon, Faruqi Nafis Ahmad, Pinto Maria Jose Wiseman, Rodrigues Savio. Isolation of Multi Drug Resistant Mycobacteria from Extrapulmonary samples in a Tertiary Care Hospital: A Retrospective Analysis. Annals of International medical and Dental Research. 2018 Mar; 4(2): 4-72395-28222395-2814http://imsear.searo.who.int/handle/123456789/188489Background: Drug resistant tuberculosis has frequently been encountered in India. The prevalence of extrapulmonary multi drug resistant tuberculosis in this country is found to be 3% in new cases and 12-17% in treated cases, which needs to be evaluated. Settings and Design: A retrospective analysis of processed extrapulmonary tubercular samples in Intermediate Reference Laboratory of Department of Microbiology, Goa Medical College, was carried out over a period of one year, from November 2013 to October 2014. Methods: Lowenstein Jensen Media was used for culture processing of 202 samples from clinically suspected cases of extra-pulmonary tuberculosis patients. Drug susceptibility testing was done on the isolated strains using the economic variant of proportion method. Results: Out of 202 samples, 30 (14.85%) were observed to be culture positive for Mycobacterium tuberculosis of which six (21.43%) were found to be resistant to both Isoniazid and Rifampicin. Conclusion: With the advent of immunocompromised states, one has to be aware of multi drug resistant extra-pulmonary tuberculosis as a double edged sword. The early detection in such cases is a need of the hour to initiate prompt treatment.Journal ArticleIndiaMD Microbiology, Senior Resident, Department of Anatomy, JN Medical College, Aligarh Muslim University, Aligarh 202002, India, Senior Consultant RNTCP, IRL, Goa Medical College (past affiliation)M.D. Microbiology, District Microbiologist, Integrated Disease Surveillance Project , Margao, South Goa.MS. Anatomy, Professor, Department of Anatomy, JN Medical College, Aligarh Muslim University, Aligarh 202002, India.Associate Professor,Department of Microbiology , Goa Medical College, Bambolim.Professor and Head , Department of Microbiology , Goa Medical College, Bambolim.