Louisirirotchanakul, SWasi, CSatrasook, SSurakhaka, MThongcharoen, P2009-05-272009-05-271984-09-01Louisirirotchanakul S, Wasi C, Satrasook S, Surakhaka M, Thongcharoen P. Rotavirus in pediatric diarrhoea at Siriraj Hospital, Bangkok, Thailand. The Southeast Asian Journal of Tropical Medicine and Public Health. 1984 Sep; 15(3): 348-53http://imsear.searo.who.int/handle/123456789/30768The Southeast Asian Journal of Tropical Medicine and Public Health.Between June 1982 and May 1983, rotavirus was found in 29% of 248 pediatric patients between 1 month to 5 years of age at Siriraj Hospital, Bangkok, Thailand. Among 413 household contacts, RV was detected in 9 (2%) of whom 6 developed diarrhoea. RV was not found in age-matched healthy controls. In a serological study, the serological response was 81% in rotavirus diarrhoea cases (17 out of 21) by ELISA. By the ELISA blocking test, the seroconversion rate was only 29.6% in rotavirus diarrhoea cases (8 out of 27) and in others, 2 out of 71 cases (2.6%) who also showed serological response did not have rotavirus in their stools. This study indicates role of rotavirus in causing acute diarrhoea in young children, suggests a guideline for diagnosis and management of the patients. The rotavirus immunization should be considered if the vaccine becomes available in the near future.engAcute DiseaseAntibodies, Viral --biosynthesisChild, PreschoolDeveloping CountriesDiarrhea --etiologyDiarrhea, Infantile --etiologyHumansInfantRotavirus --immunologyRotavirus Infections --epidemiologyThailandComparative Study