Chakraborty, R NBidwai, P SKak, V KBanarjee, A KKhattri, H NSapru, R PWalia, B NKumar, LSuri, SWahi, P L1989-05-012009-05-271989-05-012009-05-271989-05-01Chakraborty RN, Bidwai PS, Kak VK, Banarjee AK, Khattri HN, Sapru RP, Walia BN, Kumar L, Suri S, Wahi PL. Brain abscess in cyanotic congenital heart disease. Indian Heart Journal. 1989 May-Jun; 41(3): 190-3http://imsear.searo.who.int/handle/123456789/3053Twenty-eight patients of cyanotic congenital heart disease (CHD) complicated with brain abscess were reviewed. There were 22 males and 6 females with a mean age of 9.1 +/- 5.5 years. Tetralogy of Fallot was the commonest cyanotic CHD observed. Transposition of great arteries (PS), tricuspid atresia with VSD, PS and double outlet right ventricle with VSD comprised 25% of the cardiac lesions. Febrile illness was the commonest mode of presentation (42.86%). Frontal lobe was the commonest site of abscess localization (37.5%) followed by parietal lobe (32.5%). Multiple abscess were seen in 32.14% and in 35.7% the pus was sterile on culture. Twelve patients died (mortality -42.8%), and autopsy reports were available in 6. Infective endocarditis was suspected in 7 on clinical grounds, while at autopsy, out of 6 only 2 had evidence of right-sided endocarditis. There was no correlation of mortality with age, sex, type of micro-organism, site of abscess localization and the nature of heart disease. Multiple abscesses, features of raised intracranial tension and associated meningitis/ventriculitis predicted a grim outcome.engBrain Abscess --complicationsChildFemaleHumansMaleTetralogy of Fallot --complicationsJournal Article