Tanwandee, TawesakPiratvisuth, TeerhaPhornphutkul, KannilkaMairiang, PisalnPermpikul, ParichartPoovorawan, Yong2009-05-272009-05-272006-11-28Tanwandee T, Piratvisuth T, Phornphutkul K, Mairiang P, Permpikul P, Poovorawan Y. Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study. Journal of the Medical Association of Thailand. 2006 Nov; 89 Suppl 5(): S79-83http://imsear.searo.who.int/handle/123456789/44613Chotmaihet Thangphaet.OBJECTIVE: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand MATERIAL AND METHOD: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated by using conditional logistic regression. RESULTS: The final multivariable model included only the following independent HCVrisk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. CONCLUSION: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection.engBlood DonorsCase-Control StudiesCross-Sectional StudiesDemographyHealth SurveysHepatitis C --bloodHumansInterviews as TopicRisk AssessmentRisk FactorsSeroepidemiologic StudiesThailand --epidemiologyJournal Article