Sudeep, A BJadi, R SMishra, A C2011-12-162011-12-162009-11Sudeep A B, Jadi R S, Mishra A C. Ganjam virus. Indian Journal of Medical Research. 2009 Nov; 130(5): 514-519.http://imsear.searo.who.int/handle/123456789/135931Ganjam virus (GANV), a member of genus Nairovirus of family Bunyavirdae is of considerable veterinary importance in India. Though, predominantly tick borne, GANV was also isolated from mosquitoes, man and sheep. Neutralizing and complement fixing antibodies to GANV have been detected in animal and human sera collected from different parts of the country. Thirty three strains of GANV have been isolated from India, mainly from Haemaphysalis ticks. The virus replicated in certain vertebrate and mosquito cell lines and found pathogenic to laboratory animals. One natural infection and five laboratoryacquired infections in men were also reported. GANV is antigenically related to Nairobi sheep disease virus (NSDV) of Africa, which is highly pathogenic for sheep and goats causing 70-90 per cent mortality among the susceptible population. Recent molecular studies have demonstrated that GANV is an Asian variant of NSDV and both these viruses are related to the dreaded Crimean Congo haemorrhagic fever (CCHF) group viruses. The versatility of the virus to replicate in different arthropod species, its ability to infect sheep, goat and man makes it an important zoonotic agent.enGanjam virusHaemaphysalis intermediaNairobi sheep diseaseNairovirustickAnimalsBunyaviridae Infections --transmissionBunyaviridae Infections --virologyFemaleGoatsHumansIndiaMaleMiceNairobi Sheep Disease --virologyNairobi sheep disease virus --geneticsNairobi sheep disease virus --isolation & purificationNairobi sheep disease virus --pathogenicityNairobi sheep disease virus --physiologySheepTicks --virologyVirus ReplicationZoonoses --transmissionZoonoses --virologyArticle