Handal, AAwake, PKulkarni, DKhobragade, S2023-08-092023-08-092023-03Handal A, Awake P, Kulkarni D, Khobragade S. A Case of Lepromatous Leprosy with Laryngeal Involvement Presenting as Dysphonia. Indian Journal of Leprosy. 2023 Mar; 95: 81-850254-9395http://imsear.searo.who.int/handle/123456789/222631Involvement of larynx is a uncommon manifestation but could be the first time when the patient may be reporting to a specialist. This is the case report of a 65-year-old man who presented with dysphonia, was evaluated and was diagnosed as lepromatous leprosy with laryngeal involvement. On clinical examination the patient was found to have signs of leprosy – leonine face, nodular involvement of ears, madarosis, oedema of hands and feet, trophic ulcer on right foot. Bilateral greater auricular nerves were found to be enlarged. Video laryngoscopy revealed pale edematous epiglottis, arytenoid and aryepiglottic folds, with nodules on epiglottis. Biopsy from aryepiglottic fold and skin both was done. The diagnosis of lepromatous leprosy was confirmed with histopathology of biopsy from both skin and epiglottic fold. MRI imaging of the neck with contrast showed diffuse hyperintensity in the glottic-supraglottic larynx with asymmetry in the aryepiglottic fold and vocal cord. This experience shows that clinical suspicion is most critical element in reaching the diagnosis of leprosyLepromatous LeprosyLaryngeal InvolvementDysphoniaA Case of Lepromatous Leprosy with Laryngeal Involvement Presenting as DysphoniaJournal ArticleIndiaAssistant Professor, Department of OtorhinolaryngologyAssistant Professor, Department of Dermatology, Venereology and LeprosyJunior Resident, Department of OtorhinolaryngologyJunior resident, Department of Otorhinolaryngology Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune-412115, Maharashtra, India.