Kothari, S SKumar, R KVarma, SSaxena, A1996-05-012009-05-271996-05-012009-05-271996-05-01Kothari SS, Kumar RK, Varma S, Saxena A. Thrombolytic therapy in infants for femoral artery thrombosis following cardiac catheterisation. Indian Heart Journal. 1996 May-Jun; 48(3): 246-8http://imsear.searo.who.int/handle/123456789/3852Little information is available on the use of thromobolytic therapy in infants for femoral artery thrombosis after cardiac catheterisation. We report 12 cases (mean age: 4 months; range: 1-9 months) who received intravenous streptokinase (3000 U/kg bolus, 1000 U/kg/h) infusion. Five of them had undergone transarterial balloon dilatation procedures. Streptokinase was administered 48 h after catheterisation and continued for 4-20 h (mean 11.5 h). No detailed haematologic monitoring was done during therapy. Distal pulses were restored in all the patients. No complications were seen except a minor local ooze in two patients. We found that intravenous streptokinase is a safe and effective therapy for femoral artery thrombosis following cardiac catheterisation in infants.engFemoral ArteryFibrinolytic Agents --therapeutic useHeart Catheterization --adverse effectsHumansInfantStreptokinase --therapeutic useThrombolytic TherapyThrombosis --drug therapyTreatment OutcomeJournal Article