Boonrert Pealskulrat2011-02-222011-02-222011-02-012011-02-01Mahasarakham Hospital Journal; Vol.6 No.4 February - April 2010; 19-25http://imsear.searo.who.int/handle/123456789/131662Chronic suppurative otitis media (CSOM) is a disease well known to otolaryngologists. It is a chronic inflammatory process, slow and insidious in its course, tend to be persistent, with sometimes irreversible sequelae. The aerobic microbiology of 59 patients from Lampang Hospital, who suffered from chronic suppurative otitis media was studied between January 2008 and March 2009.  A total of 57  isolates (45 singled isolates and 6 mixed isolates) were recovered. The predominant organisms were Pseudomonas aeruginosa(30.5%), Staphylococcus coagulase negative(10.1%) and Staphylococcus aureus(6.8%).  Many of Staphylococcus sp.  can produce beta-lactamase, rendering them resistant to many of the penicillins. A knowledge of the pathogens responsible for CSOM can assist in the selection of the most appropriate treatment regimen and can minimize complications.en-USMahasarakham Hospital, Mahasarakham, Ministry of Public Health, ThailandArticles