Pasricha, SunilDurga, GarimaSharma, AnilaJajodia, AnkushSingh, ShivendraGupta, GuruduttKamboj, MeenakshiKoyyala, Venkata Pradeep BabuGupta, ManojMehta, Anurag2024-11-302024-11-302024-01Pasricha Sunil, Durga Garima, Sharma Anila, Jajodia Ankush, Singh Shivendra, Gupta Gurudutt, Kamboj Meenakshi, Koyyala Venkata Pradeep Babu, Gupta Manoj, Mehta Anurag . Extranodal follicular dendritic cell sarcoma presenting as colonic mass: A diagnostic and therapeutic challenge. Journal of Cancer Research and Therapeutics. 2024 Jan; 20(1): 450-4530973-14821998-4138https://imsear.searo.who.int/handle/123456789/238186Folliclular dendritic cell sarcoma (FDCS) is an extremely rare neoplasm originating from folliclular dendritic cells, both nodally and extranodally. Its primary presentation as a large colonic mass is rare and can be misdiagnosed as epithelial tumor/soft tissue tumor both clinically and through histomorphology. Due to its rarity and limited consensus guidelines about its management, it presents as a diagnostic and therapeutic challenge for pathologists and oncologists. However, accurate diagnosis is imperative due to its distinct prognostic and therapeutic implications. Herein we report, two cases of extranodal FDCS of colon with the aim of contributing to the management of this uncommon entity.CD21CD23folliclular dendritic cell sarcomagastrointestinal tractExtranodal follicular dendritic cell sarcoma presenting as colonic mass: A diagnostic and therapeutic challengeJournal ArticleIndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Radiology, Juravinski Hospital, McMaster University, CanadaDepartment of Gastrointestinal Oncosurgery, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IndiaDepartment of Medical Oncology, Assam Cancer Care Foundation, Assam, IndiaDepartment of Nuclear Medicine, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, India