Abdul Samad, KPrasanna, Moorthy KAkhar, Ali P2009-05-282009-05-282002-07-28Abdul Samad K, Prasanna MK, Akhar AP. Sezary syndrome--without erythroderma. Indian Journal of Dermatology, Venereology and Leprology. 2002 Jul-Aug; 68(4): 225-6http://imsear.searo.who.int/handle/123456789/52509Sezary syndrome (SS), is described as the classical triad of pruritic erythroderma, lymphadenopathy, and presence of more than 10% of circulating Sezary cells in the peripheral blood. We report on unusual case of advanced cutaneous T - cell lymphoma with classical haematological and histopathological features of Sezary syndrome, but lacking the clinical features of erythroderma. A 66 year old man presented with asymptomatic multiple papules, plaques and nodules and with generalized lymphadenopathy. Peripheral smear showed more than 60% of Sezary cells. Skin and lymph node biopsy showed typical features of T-cell lymphoma and immunohistochemistry and CD marker studies showed the cells to be atypical T-lymphocytes. This unusual case is highlighted to denote that erythroderma need not be taken as a hard and fast criterion for diagnosing Sezary syndrome.engJournal Article