Sharada, SathishVijayakumar, MahalingamNageswaran, PrahladEkambaram, SudhaUdani, Amish2016-01-212016-01-212014-08Sharada Sathish, Vijayakumar Mahalingam, Nageswaran Prahlad, Ekambaram Sudha, Udani Amish. Multicystic Dysplastic Kidney: A Retrospective Study. Indian Pediatrics. 2014 Aug; 51(8): 641-643.http://imsear.searo.who.int/handle/123456789/170727Objective: To report the renal structural and functional anomalies in children with multicystic dysplastic kidneys. Methods: Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years. Results: Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%) patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4 [13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux (n=13; 28%) was the commonest renal abnormality. The serum creatinine values were higher (P=0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%) and was significantly associated with complete involution (P=<0.023). None of the patients developed hypertension and 2 (6.4%) had renal failure. Conclusion: Close nephrological follow-up is needed in children with multicystic dysplasia of kidneys.enHyperfiltration injuryMulticystic dysplastic kidneyProteinuriaMulticystic Dysplastic Kidney: A Retrospective Study.Article