Munshi, AMehrotra, RPanda, S K1994-04-012009-06-041994-04-012009-06-041994-04-01Munshi A, Mehrotra R, Panda SK. Characterisation of the Indian strain of duck hepatitis B virus (DHBV) and development of a carrier duck colony for antiviral drug testing. Tropical Gastroenterology. 1994 Apr-Jun; 15(2): 77-85http://imsear.searo.who.int/handle/123456789/125271Duck hepatitis B virus (DHBV) infected carrier ducks serve as a useful model for testing anti-hepadnavirus drugs. This needs a well characterised duck hepatitis B virus strain. We cloned and sequenced the complete genome of duck hepatitis B virus strain of Indian origin. It was 3021 nucleotides in length and had all the recognisable open reading frames (Polymerase: 20-2530 nucletides, Surface: 693-1787 nucleotides and Core: 2518-412). Using an inoculum of 50 microliters serum containing 1 x 10(11) virus particles/ml, we could infect 80% of one day old ducklings and develop a duck colony.engAnimalsAntiviral Agents --pharmacologyBase SequenceDucksGenome, ViralHepadnaviridae Infections --drug therapyHepatitis B Virus, Duck --drug effectsMolecular Sequence DataCharacterisation of the Indian strain of duck hepatitis B virus (DHBV) and development of a carrier duck colony for antiviral drug testing.Journal Article