Govindrao, Asolkar GeetaVithalrao, Nikam AshwinVenkatrao, Pawade UdayPramodrao, Anjankar Meghsham2023-08-092023-08-092023-02Govindrao Asolkar Geeta, Vithalrao Nikam Ashwin, Venkatrao Pawade Uday, Pramodrao Anjankar Meghsham. A PRECLINICAL STUDY ON EVALUATION OF ANTICANCER ACTIVITY OF SNUHI KSHARA IN HUMAN COLON CANCER CELL LINE HCT-15. Indian Journal Of Applied Research. 2023 Feb; 13(2): 33-352249-555Xhttp://imsear.searo.who.int/handle/123456789/221355Snuhi (Euphorbia neriifolia Linn.) is a conventional herb used broadly in several disease conditions as indicated in classical texts of Ayurveda. As per literature review ascertained, no literature was accessible regarding anticancer activity of Snuhi Kshara. Thus, present work was designed to evaluate the anticancer activity of Snuhi Kshara in HCT-15 (Human Colon Cancer cell line). Anticancer activity was evaluated using MTT assay by % cell viability and IC50. Anticancer activity was compared with standard drug capecitabine. A positive correlation between Concentration and % cell viability was noticed. Lowest cell viability was noted at 5000 µg concentration. Results obtained through the study indicates towards anticancer activity of Snuhi Kshara.Ayurveda AgadtantraSnuhi (Euphorbia neriifolia Linn.)Snuhi Kshara (SK)AnticancerIn VitroMTT assay% cell viabilityIC .Journal ArticleIndiaP. D. E. A'S College of Ayurved & Research Centre, Nigdi, Pune - 411044, Maharashtra, India. *Corresponding AuthorShri Ayurved Mahavidyalaya, Hanuman Nagar, Nagpur - 440024, Maharashtra, IndiaShri Ayurved Mahavidyalaya, Hanuman Nagar, Nagpur - 440024, Maharashtra, IndiaShri Ayurved Mahavidyalaya, Hanuman Nagar, Nagpur - 440024, Maharashtra, India.