Agarwal, DeeptiAwasthi, SeemaDutta, Shyamoli2016-03-082016-03-082016-01Agarwal Deepti, Awasthi Seema, Dutta Shyamoli. Accuracy of Cytological Analysis in Metastatic Lymphadenopathy; a Retrospective Study. Annals of International Medical and Dental Research. 2016 Jan-Feb; 2(1): 89-93.http://imsear.searo.who.int/handle/123456789/175388Background: Presently, fine needle aspiration (FNA) biopsy is the preliminary, non-invasive test for diagnosis of suspected lymphadenopathy. Apart from its diagnostic yield, it helps identifying the origin, grading and typing of the metastatic lesions in many cases. Methods: In the present study, data of 369 patients with suspected neoplastic lymphadenopathy presenting to the surgical and medical outpatient department of our institute over a period of 3 years was collected. FNA biopsy was performed on the most prominently visible and palpable lymph node. The use of special stains was performed in selected cases. Results: Of 369 cases studied, cytological diagnosis was offered in 358 cases, while unsatisfactory smears were reported in 11 cases. Of these 358 cases where a cytological diagnosis of either primary or metastatic lymphadenopathy was given, 244 were males and 114 were females. Metastatic tumors in the lymph nodes were reported in 307 cases and lymphoma in 51 cases. The distribution of lymphadenopathy revealed involvement of cervical group in 222 cases, axillary group in 57 cases, supraclavicular in 28 cases & inguinal in 24 cases. The commonest primary tumor, metastasizing to lymph nodes was squamous cell carcinoma (52.44%). Conclusion: In our study, FNA biopsy proved to be a safe and non-expensive technique that provided a high diagnostic accuracy with zero false positive results, confirmed the presence of secondaries where primary tumor was evident and guided the response to medical treatment.enFine needle Aspiration (FNA) BiopsymetastaticlypmhadenopathylymphomacytologyArticle