Beg, SamanFirdaus, UzmaAli, Syed Manazir2025-05-092025-05-092024-09Beg Saman, Firdaus Uzma, Ali Syed Manazir . Cord Blood Bilirubin as a Predictor of Neonatal Hyperbilirubinemia. Acta Medica International. 2024 Sep; 11(3): 209-2122349-05782349-0896https://imsear.searo.who.int/handle/123456789/245744Introduction: In the 1st week of life, hyperbilirubinemia is the most common clinical condition in newborns that has to be evaluated and treated. It is also a prominent cause of readmission to the hospital. Some newborns experience noticeable, potentially dangerous bilirubin levels, which can directly increase the risk of severe brain damage, despite it being a benign, postnatal, transitory phenomenon. The current investigation looked at the relationship between cord blood bilirubin levels and the predictability of pathological jaundice. Materials and Methods: Cord blood bilirubin was estimated at birth. Bilirubin estimation was done at 48 h, 72 h, and 5–7 days of life using a trans?bilirubinometer. The study was approved by the Institutional Ethical Committee. Results: Significant hyperbilirubinemia was found in 3.7% of the neonates. A statistically significant correlation was found between cord blood bilirubin and the development of significant hyperbilirubinemia at 48 h of life. Gender, gestational age, birth weight, and use of Oxytocin have no correlation with cord bilirubin or the subsequent development of jaundice. A cord blood value of >2 mg/dL has a high negative predictive value (98%), sensitivity (83%), specificity (41%), and positive predictive value (5.3%) in predicting the future development of future pathological jaundice. Conclusions: A high negative predictive value in our study suggests that healthy term babies with cord bilirubin ?2 mg/dL can be discharged early with assurance to parents. Babies with cord blood bilirubin >2 mg/dL should be followed more frequently.Cord blood bilirubinhigh negative predictive valuehyperbilirubinemiatrans?bilirubinometerJournal ArticleIndiaDepartment of Pediatrics, Career Institute of Medical Sciences and Hospital, Lucknow, Uttar Pradesh, IndiaDepartment of Pediatrics, J. N. Medical College and Hospital, AMU, Aligarh, Uttar Pradesh, IndiaDepartment of Pediatrics, J. N. Medical College and Hospital, AMU, Aligarh, Uttar Pradesh, India