Gnanasekaran, TVijayakumar, PRethinavelu, CTharkade, Nikhil2023-07-212023-07-212023-03Gnanasekaran T, Vijayakumar P, Rethinavelu C, Tharkade Nikhil. HISTOLOGICAL VARIANTS OF BLADDER TUMORS : DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC IMPLICATIONS – A CASE SERIES. Global Journal For Research Analysis . 2023 Mar; 12(3): 15-172277-8160http://imsear.searo.who.int/handle/123456789/220704Bladder cancer is one of the leading malignancies in the world associated with signi?cant morbidity and mortality. About 80% of a bladder cancer is urothelial variant, remaining 20% will have a divergent histological presentation. The pathophysiological study of these variants has recently increased because the therapeutic approach is not uniform for all variants. These variants have important diagnostic, prognostic and therapeutic implications. A molecular and genetic study of these variants will allow them to be better de?ned. Here we present four cases of Histological variants of bladder tumors with varying presentations in the department of urology, Madurai medical college, which is studied over the period of one year (2022-2023).In?ammatory myo?broblastic tumorInvasive Urothelial carcinoma with squamous differentiationUrothelial papillomaCystitis cystica.Journal ArticleIndiaAssociate Professor, Madurai Medical College, MaduraiPost Graduate, Madurai Medical College, Madurai. *Corresponding Author