Islam, NSinha, DGhosh, PDatta, CChatterjee, U2020-04-102020-04-102018-12Islam N, Sinha D, Ghosh P, Datta C, Chatterjee U. Orchitis: An unusual presentation of polyarteritis nodosa. Indian Journal of Pathology and Microbiology. 2018 Dec; 61(4): 600-6030377-49290974-5130http://imsear.searo.who.int/handle/123456789/196266Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population.Epididymo-orchitispolyarteritis nodosavasculitisJournal ArticleIndiaDepartment of Pathology, IPGME and R, Kolkata, West Bengal, IndiaDepartment of Rheumatology, IPGME and R, Kolkata, West Bengal, India