Nnodim, John KennedySamuel, MeluduDioka, C EOnah, Christian EjikeIhim, AugustineAtuegbu, Chidiadi2016-03-082016-03-082014-08-21Nnodim John Kennedy, Samuel Meludu, Dioka C E, Onah Christian Ejike, lhim Augustine, Atuegbu Chidiadi. Trace Elements Deficiency in Patients with Homozygous Sickle Cell Disease. British Journal of Medicine and Medical Research. 2014 July; 4(21): 3878-3883.http://imsear.searo.who.int/handle/123456789/175332Aim: The serum trace elements statuses of sickle cell patients attending at General Hospital Owerri, Nigeria were investigated to determine whether or not the serum levels of these elements were normal. Materials and Methods: One hundred confirmed sickle cell patients (HbSS) age 5–30 years were selected. One hundred normal subjects (HbAA) age 5–30 years were used as control. Results: The levels of trace elements were significantly decreased in sickle cell anemia (p<0.05), except copper, when compared with the control. Conclusion: The result suggests, but not conclusively, that supplementation of sickle cell patients with food and drug containing trace elements might be helpful, particularly if diminished mineral levels predispose patients to crises.enTrace elementsdeficiencyhomozygous sickle cell diseaseArticle