Singla, Mani KantLahiri, PrabirMukhopadhyay, PradipPandit, KaushikChaudhuri, UtpalChowdhury, Subhankar2008-11-172009-05-312008-11-172009-05-312008-11-17Singla MK, Lahiri P, Mukhopadhyay P, Pandit K, Chaudhuri U, Chowdhury S. A study of aspirin resistance in type 2 diabetes. Journal of the Indian Medical Association. 2008 Nov; 106(11): 720, 722-3, 740http://imsear.searo.who.int/handle/123456789/99640Aspirin is currently known to give inadequate protection against coronary artery disease in diabetes compared to person without it. We evaluated 97 consecutive patients with type 2 diabetes for assessing laboratory aspirin resistance and attempted to assess the impact of various clinical and biochemical parameters on it. Thirty-eight patients (39.1%) were found to be less sensitive to the action of aspirin, 7 persons (7.2%) were found to be resistant and 31 persons (31.9%) were aspirin semi-responders. Only total cholesterol, LDL-cholesterol and triglyceride had statistically significant impact on aspirin resistance (p<0.05). Three persons out of 9 with some form of macrovascular disease had aspirin resistance.engAspirin --administration & dosageCholesterol, LDL --bloodCoronary Artery Disease --bloodDiabetes Mellitus, Type 2 --bloodDiabetic Angiopathies --bloodDrug ResistanceHumansMiddle AgedPlatelet Aggregation --drug effectsPlatelet Aggregation Inhibitors --administration & dosagePlatelet Function TestsRisk FactorsTriglycerides --bloodJournal Article