Swarnaakshari, S.Meitei, Lourembam RomenSharma, B. BobbyJaleshwar, LaishramDeepak, Minjur IlangoSharma, M. BirkumarSingh, Th. Suraj2025-05-092025-05-092024-09Swarnaakshari S., Meitei Lourembam Romen, Sharma B. Bobby, Jaleshwar Laishram, Deepak Minjur Ilango, Sharma M. Birkumar, Singh Th. Suraj . Accelerating Healing: The Impact of Negative Pressure Wound Therapy on Diabetic Foot Ulcers. International Journal of Contemporary Medical Research. 2024 Sep; 11(9): 1-62393-915X2454-7379https://imsear.searo.who.int/handle/123456789/246167Diabetic foot ulcers, a prevalent global health issue, often necessitate hospitalization due to prolonged healing times and complications. This study aimed to compare the efficacy of Negative Pressure Wound Therapy (NPWT) with Standard Moist Wound Therapy (SMWT) in treating diabetic foot ulcers. Conducted over two years at the Regional Institute of Medical Sciences, Imphal, the study enrolled 40 patients with chronic diabetic foot ulcers. The NPWT group, receiving continuous sub-atmospheric pressure via a vacuum pump, demonstrated superior outcomes compared to the SMWT group. Specifically, the NPWT group achieved 97.25% granulation tissue formation within three weeks, compared to 83% in the SMWT group, and had a significantly reduced hospital stay duration (mean 12.6 days vs. 38.3 days). Additionally, NPWT led to better glycaemic control and improved renal function. These results suggest that NPWT enhances wound healing, reduces hospital stay, and is a cost- effective alternative to traditional wound management. The study supports the use of NPWT as a recommended treatment for diabetic foot ulcers in hospital settings.Chronic Limb UlcerDiabeticsExtricare 2400Glycaemic ControlGranulation TissueNegative Pressure Wound TherapyVacuum-assisted Closure.Journal ArticleIndiaPost Graduate Trainee 3rd year, Department Name - Department of General Surgery, Regional Institute of Medical Sciences ImphalProject Associate, Department of Multi-Disciplinary Research Unit, Regional Institute of Medical Sciences ImphalAssistant Professor, Department of General Surgery, Regional Institute of Medical Sciences ImphalAssistant Professor, Department of General Surgery, Regional Institute of Medical Sciences ImphalAssistant Professor, Department of General Surgery, Pondicherry Institute of Medical SciencesProfessor, Department of General Surgery, Regional Institute of Medical Sciences ImphalHOD, Department of Neurology, Regional Institute of Medical Sciences Imphal