Swain, John2009-05-282009-05-282008-05-14Swain J. Mode coupling in living systems: implications for biology and medicine. Indian Journal of Experimental Biology. 2008 May; 46(5): 389-94http://imsear.searo.who.int/handle/123456789/56315Complex systems, and in particular biological ones, are characterized by large numbers of oscillations of widely differing frequencies. Various prejudices tend to lead to the assumption that such oscillators should generically be very weakly interacting. This paper reviews the basic ideas of linearity and nonlinearity as seen by a physicist, but with a view to biological systems. In particular, it is argued that large couplings between different oscillators of disparate frequencies are common, being present even in rather simple systems which are well-known in physics, although this issue is often glossed over. This suggests new experiments and investigations, as well as new approaches to therapies and human-environment interactions which, without the concepts described here, may otherwise seem unlikely to be interesting. The style of the paper is conversational with a minimum of mathematics, and no attempt at a complete list of references.engAcousticsBiophysics --methodsElectromagnetic FieldsEnvironmentFourier AnalysisModels, TheoreticalOscillometry --methodsPhotonsResearch DesignSystems Biology --methodsJournal Article