Goyal, MGoel, AKumar, PBajpai, MVerma, N SKant, STiwari, S2008-01-042009-06-012008-01-042009-06-012008-01-04Goyal M, Goel A, Kumar P, Bajpai M, Verma NS, Kant S, Tiwari S. Circadian rhythm of peak expiratory flow rate in healthy north Indian men. Indian Journal of Physiology and Pharmacology. 2008 Jan-Mar; 52(1): 64-8http://imsear.searo.who.int/handle/123456789/106741Peak expiratory flow rate (PEFR) variability follows a specific pattern in asthmatics as well as in healthy individuals. There is scarcity of data for Indian healthy subjects. The PEFR (L/min.) was measured with Wright's portable peak flow meter at 05:00, 8:00, 11:00, 14:00, 17:00, 20:00 and 23:00 hours in 42 healthy, non-smoking adults of age group between 18-26 years. The variability of PEFR revealed a circadian pattern. PEFR levels tend to increase from morning at 5:00 hours till evening at 17:00 hours, with peak PEFR in evening at 17:00 hours, after which there was a progressive fall in PEFR levels, till morning 5:00 hours. This study provides the preliminary reference data of circadian pattern of PEFR in healthy individuals.engAdolescentAdultCircadian Rhythm --physiologyHumansIndiaMalePeak Expiratory Flow Rate --physiologyReference ValuesJournal Article