Saneetantikul, OpalSongsaeng, DittapongChurojana, AnchaleeChiewvit, PipatChawalparit, OrasaSuthipongchai, Suthisak2012-02-072012-02-072007-03Saneetantikul Opal, Songsaeng Dittapong, Churojana Anchalee, Chiewvit Pipat, Chawalparit Orasa, Suthipongchai Suthisak. Cranial dural arteriovenous fistula: Predisposing factors to aggressive symptoms. Siriraj Medical Journal, 2007 Mar; 59(3): 114-118.http://imsear.searo.who.int/handle/123456789/136775Objective: To evaluate the clinical and angiographic data of cranial dural arteriovenous fistula in Thai patients and to determine the predisposing factors to aggressive symptoms. Methods: Retrospective review of 71 patients with cranial dural arteriovenous fistula who underwent cerebral angiography at Siriraj Hospital between July 2002 – February 2006. Their clinical manifestations were classified as benign or aggressive symptoms. The relationship between aggressive symptoms and the following factors were studied: gender, location of the fistula, classification according to venous drainage pattern, presence of cerebral sinus thrombosis, and shunt multiplicity. Linear-by-linear association and chi-square test were used to determine statistical significance. Results: Sixteen (22.5%) of 71 patients with cranial dural arteriovenous fistula had aggressive presenting symptoms. Factors that significantly correlate with aggressive symptoms were location of the fistula, retrograde leptomeningeal venous drainage, presence of cerebral sinus thrombosis, and multiplicity. Factor which was not significantly correlated with aggressive symptoms was gender. Conclusion: This study evaluated clinical data and angiographic features of cranial dural arteriovenous fistula in Thai patients. Predisposing factors to aggressive symptoms were location of the fistula, retrograde leptomeningeal venous drainage, presence of cerebral sinus thrombosis, and multiplicity.enAggressive symptomscerebral sinus thrombosiscranial dural arteriovenous fistularetrograde leptomeningeal venous drainageArticle