Sehgal, Virendra N2020-01-022020-01-022018-04Sehgal Virendra N. Atopic Dermatitis: Drug Delivery (Management) and Approaches (Strategies) in Perspective. Annals of the National Academy of Medical Sciences (India). 2018 Apr; 54(2): 78-890379-038Xhttp://imsear.searo.who.int/handle/123456789/189708Age-related cutaneous manifestations are definitive pointer to the diagnosis of atopic dermatitis, the confirmation of which is solicited by 3 major and 3 minor criteria. Its unpredictable course is st nd rd punctuated by exacerbations and remissions. Several treatment options, namely: 1 , 2 and 3 line are st nd in vogue ever since. The 1 line envisages general measures, 2 encompasses topical applications, rd while the 3 take into account drug therapy comprising, systemic Corticosteroids, Cyclosporin, Azathioprine, Thymopentin, Interferon–therapy, Topical Calcineurin inhibitors: Tacrolimus and Pimecrolimus. The mode of action, their dosages and adverse drug reaction (ADR), in particular, have been focused in this paper with special attention to refresh their drug delivery (management) approaches (strategies) in perspective. An endeavor to focus attention to emerging etio-pathogenesis, and its application in the contemporary context has also been madeJournal ArticleIndiaDermato-Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, DelhiDermato Venerology (Skin/VD) Centre, Sehgal Nursing Home, A/6 Panchwati, Delhi-110 033 (India). Ph: 011-27675363, 9810182241. Email: drsehgal@ndf.vsnl.net.in