Gupta, AnuragGoyal, ManuNidamanuri, Koteswara RaoDattatreya, Palanki Satya2015-02-122015-02-122014-01Gupta Anurag, Goyal Manu, Nidamanuri Koteswara Rao, Dattatreya Palanki Satya. Your dilemma, my identity: Unusual immunogenetic profiles of pediatric B cell acute lymphoblastic leukemia. Indian Journal of Pathology & Microbiology. 2014 Jan-Mar 57 (1): 78-80.http://imsear.searo.who.int/handle/123456789/155973B-cell acute lymphoblastic leukemia (B-ALL) is characterized by CD19 expression, which is one of the most important prerequisites, along with expression of CD10, CD22 and/or CD79a. Rearrangements involving MLL gene are seen in CD10− B-ALL (pro-B cell origin) and t(9;11)(p21;q23) is most commonly reported in acute myeloid leukemia (AML), where it is known to carry very good prognosis in pediatric AMLs and rarely in acute lymphoblastic leukemia (ALL). We report a case of CD10+, CD19− pediatric ALL with rearrangements of MLL gene as a result of t(9;11)(p21;q23), thus conferring a very poor prognosis. The case emphasizes use of comprehensive panel of antibodies for fl ow cytometric immunophenotyping and cytogenetic correlation for correct diagnosis and prognostication. KEY WORDS: Acute lymphoblastic leukemia, CD19, MLL gene, t(9;11)(p21;q23)enAcute lymphoblastic leukemiaCD19MLL genet(9;11)(p21;q23)Article