Guo, LingchenJiang, MinMa, YushuCheng, HaipengNi, XiaohuaJin, YangshengXie, YiMao, Yumin2002-04-032009-06-022002-04-032009-06-022002-04-03Guo L, Jiang M, Ma Y, Cheng H, Ni X, Jin Y, Xie Y, Mao Y. Cloning, chromosome localization and features of a novel human gene, MATH2. Journal of Genetics. 2002 Apr; 81(1): 13-7http://imsear.searo.who.int/handle/123456789/114489We report cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2. Results of Northern blot analysis revealed two transcripts of the MATH2 gene of 1.7 kb and 2.4 kb in human brain. We localized MATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. Human MATH2 and mouse Math2 may have the same functions in the nervous system.engAmino Acid SequenceAnimalsBase SequenceBasic Helix-Loop-Helix Transcription FactorsChromosome MappingChromosomes, Human, Pair 7 --geneticsCloning, MolecularDNA, Complementary --geneticsHelix-Loop-Helix Motifs --geneticsHumansMiceMolecular Sequence DataNerve Tissue ProteinsSequence Homology, Amino AcidTranscription Factors --geneticsJournal Article