Raj, Napa DelhiRao, Abburu RukmangadaBhimanadhuni, Chusena Narasimharaju2015-12-112015-12-112012Raj Napa Delhi, Rao Abburu Rukmangada, Bhimanadhuni Chusena Narasimharaju. Development of RP-HPLC method for the estimation of Rasagiline mesylate in bulk and tablet dosage forms. International Current Pharmaceutical Journal. 2012; 1(9): 285-287.2224-9486http://imsear.searo.who.int/handle/123456789/167872A simple RP-HPLC method for the determination of Rasagiline Mesylate in bulk and tablet dosage form was devel-oped. Numerous HPLC conditions were tested for determination of rasagiline. The best result was achieved by using Purosphere star RP-18, (150×4.6mm), 5μm column and a mobile phase consisting of Potassium Orthophosphate: Acetonitrile (60:40 v/v) adjusted to pH 7.0(±0.05) with Ammonia solution, a flow rate of 1.5 ml/min with ultraviolet detection at 210nm. The correlation coefficients for calibration curves within the detection range of 5-30μg/ml were 0.9993. The within and between-day precision was determined for both retention time and peak area. The retention time of rasagiline is 6.0 minutes.enRasagilinePurosphere star RP-18TabletsEstimationRP-HPLCValidationMethod developmentArticle