Rajalakshmi, RamachandranPrathiba, VijayaraghavanMohan, Viswanathan2016-11-302016-11-302016-1Rajalakshmi Ramachandran, Prathiba Vijayaraghavan, Mohan Viswanathan. Does tight control of systemic factors help in the management of diabetic retinopathy. Indian Journal of Ophthalmology. 2016 Jan; 64(1): 62-68.http://imsear.searo.who.int/handle/123456789/179079Diabetic retinopathy (DR), one of the leading causes of preventable blindness, is associated with many systemic factors that contribute to the development and progression of this microvascular complication of diabetes. While the duration of diabetes is the major risk factor for the development of DR, the main modifiable systemic risk factors for development and progression of DR are hyperglycemia, hypertension, and dyslipidemia. This review article looks at the evidence that control of these systemic factors has significant benefits in delaying the onset and progression of DR.enControl of systemic factorsdiabetic retinopathyglycemic controlArticle