Gidaganti, ShrishailFaridi, MMANarang, ManishBatra, Prerna2020-04-232020-04-232018-03Gidaganti Shrishail, Faridi MMA, Narang Manish, Batra Prerna. Effect of Gastric Lavage on Meconium?Aspiration Syndrome and Feed Intolerance in Vigorous? Infants Born with Meconium Stained Amniotic Fluid – A?Randomized Control Trial. Indian Pediatrics. 2018 Mar; 55(3): 206-2100974-75590019-6061http://imsear.searo.who.int/handle/123456789/199039Objective: To compare the incidence of meconium aspirationsyndrome and feed intolerance in infants born through meconiumstained amniotic fluid with or without gastric lavage performed atbirth.Setting: Neonatal unit of a teaching hospital in New Delhi, India.Design: Parallel group unmasked randomized controlled trial.Participants: 700 vigorous infants of gestational age ?34 weeksfrom through meconium stained amniotic fluid.Intervention: Gastric lavage in the labor room with normal salineat 10 mL per kg body weight (n=350) or no gastric lavage (n=350).Meconiumcrit was measured and expressed as ?30% and >30%.Outcome Measures: Meconium aspiration syndrome, feedintolerance and procedure-related complications during 72 h ofobservation.Results: 5 (1.4%) infants in lavage group and 8 (2.2%) in nolavage group developed meconium aspiration syndrome (RR0.63, 95% CI 0.21, 1.89). Feed intolerance was observed in 37(10.5%) and 53 infants (15.1%) in lavage and no lavage groups,respectively (RR 0.70, 95% CI 0.47, 1.03). None of the infants ineither group developed apnea, bradycardia or cyanosis during theprocedure.Conclusion: Gastric lavage performed in the labor room does notseem to reduce either meconium aspiration syndrome or feedintolerance in vigorous infants born through meconium stainedamniotic fluid.Keywords: Neonate, Prevention, Respiratory distress, Riskfactors, Vomiting.NeonatePreventionRespiratory distressRisk factorsVomiting.Journal ArticleIndiaDivision of Neonatology, Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India