Fathoni, AhmadAgusta, Andria2020-10-162020-10-162019-04Fathoni Ahmad, Agusta Andria. Bioproduction of cytochalasin D by endophytic fungus Xylaria sp. DAP KRI-5. Journal of Applied Pharmaceutical Science. 2019 Apr; 2019 Apr: 105-1102231-3354http://imsear.searo.who.int/handle/123456789/210572Recently, endophytic fungi have attracted attention due to their ability to produce a variety of bioactive metabolites. Inthe course of our study on endophytic fungi associated with Albertisia papuana Becc, it has been found the endophyticfungus Xylaria sp. DAP KRI-5 produce cytochalasin D. Isolation of cytochalasin D was conducted by using anopen column chromatography method. The chemical structure of cytochalasin D was deduced from 1 dimension, 2dimension nuclear magnetic resonance, and ultra-performance liquid chromatography quadrupole time of flight massspectrometry analyses and also compared with the published data. The bioproduction capacity of cytochalasin D bythe fungus Xylaria sp. DAP KRI-5 was 0.05763 g/l.Isolationcharacterizationbioproductioncytochalasin Dendophytic fungusJournal ArticleIndiaResearch Center for Biology, Indonesian Institute of Sciences, Bogor, Indonesia.