Akande, TBalogun, S TAbdullahi, HOgundeko, O TRamyil, M S2016-12-142016-12-142015Akande T, Balogun S T, Abdullahi H, Ogundeko O T, Ramyil M S. Glycaemic Evaluation of Murraya koenigii in Alloxan-induced Diabetic Rabbits. International Journal of Biochemistry Research & Review 2015 7(4): 175-181.http://imsear.searo.who.int/handle/123456789/179844Background: Study was aimed to evaluate the antidiabetic activity of Murraya koenigii, a traditional medicinal plant (Curry leaf) in normoglycemic and alloxan-induced diabetes rabbits. Methods: Antidiabetic activity of aqueous extract of M. koenigii in 100, 200 300 mg/k doses was determined by estimating blood glucose before and at 1, 2, 4, 8, 24, and 72 hours post treatment intervals in treated rabbits. Results: Aqueous extract of Murraya koenigii showed a dose dependent antidiabetic activity with maximum effect established at 300 mg/kg. The extract also exhibited a significant (p<0.05) dosedependent hypoglycemic effect on normal and alloxan-induced diabetic rabbits. Conclusion: Murraya koenigii causes a reduction in blood glucose. This hypoglycemic property supports-its usein folkloric medicine as an antidiabetic agent and thus suggests a place for it in nutritional therapy in the management of diabetes mellitus and thus as an oral hypoglycaemic agent.enMurraya koenigiihypoglycemic effectalloxan-induced diabetesArticle