Naqvi, S MHasan, M2009-05-282009-05-281992-09-01Naqvi SM, Hasan M. Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation. Indian Journal of Experimental Biology. 1992 Sep; 30(9): 850-2http://imsear.searo.who.int/handle/123456789/62857Phosphamidon intoxication (2 mg/kg body wt./day for 7 days) inhibited SOD activity, but enhanced the lipid peroxidation in various CNS regions. Administration of cithiolone (8 mg/kg body wt./day, ip for 7 days), however, elevated SOD activity and depleted lipid peroxidation. Interestingly, no significant change was observed either in SOD activity or in lipid peroxidation following simultaneous administration of phosphamidon and cithiolone.engAnimalsCentral Nervous System --drug effectsLipid Peroxidation --drug effectsMalePhosphamidon --antagonists & inhibitorsRatsSuperoxide Dismutase --metabolismThiophenes --pharmacologyJournal Article