Rajangam, SHegde, SThomas, I M1997-10-062009-05-291997-10-062009-05-291997-10-06Rajangam S, Hegde S, Thomas IM. Down syndrome associated malformations. Indian Journal of Medical Sciences. 1997 Oct; 51(10): 390-3http://imsear.searo.who.int/handle/123456789/68133This paper reports the associated malformations and the clinical findings that were observed in 417 cytogenetically confirmed Down Syndrome patients. Among them congenital heart defects have occurred more frequently [75; 17.98%] than osteoarticular malformations [23; 5.52]; eye anomalies [22; 5.27%]; and gastroenterological malformations [n 16; 3.84%]. With regard to prognosis and treatment appropriate counselling has been given to Down Syndrome patients and their families.engAdolescentAdultChildChild, PreschoolDigestive System Abnormalities --epidemiologyDown Syndrome --epidemiologyEye Abnormalities --epidemiologyFemaleHeart Defects, Congenital --epidemiologyHumansIncidenceIndia --epidemiologyInfantInfant, NewbornMaleMusculoskeletal Abnormalities --epidemiologyRespiratory System Abnormalities --epidemiologyRetrospective StudiesSex DistributionJournal Article