Manjula, T SPrema, ADevi, C S2009-05-282009-05-281992-06-01Manjula TS, Prema A, Devi CS. Effect of aspirin on serum lipoprotein profile in rats subjected to myocardial stress by isoproterenol. Indian Journal of Experimental Biology. 1992 Jun; 30(6): 552-3http://imsear.searo.who.int/handle/123456789/59735The effect of isoproterenol on the levels of serum lipoprotein profile were studied in rats. Rats were treated with isoproterenol (200 mg/100 g body weight, sc twice at an interval of 24 hr) for 2 days. Aspirin was administered orally 1.2 mg/100 g body weight, daily for 60 days. Isoproterenol treated rats showed decrease in the activities of hepatic and extrahepatic lipoprotein lipase. HDL cholesterol level was found to be decreased, significantly with increase in LDL cholesterol in isoproterenol treated rats. Aspirin treated rats showed marked reversal of these metabolic changes. The lipoprotein changes were minimum in rats treated with both aspirin and isoproterenol.engAnimalsAspirin --pharmacologyIsoproterenolLipoproteins --bloodMaleMyocardial Infarction --bloodRatsRats, Inbred StrainsJournal Article