Tripathi, MukeshSingh, Prabhat KumarKumar, NareshPant, Kailash Chandra2009-01-132009-05-272009-01-132009-05-272009-01-13Tripathi M, Singh PK, Kumar N, Pant KC. Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome. Annals of Cardiac Anaesthesia. 2009 Jan-Jun; 12(1): 49-52http://imsear.searo.who.int/handle/123456789/1639The state of vasoplegia in immediate post-cardiopulmonary bypass period is characterized by severe hypotension, supranormal cardiac output, low systemic vascular resistance (SVR), and resistance to vasoconstrictors. We could successfully use induced mild hypothermia to increase SVR, and could avoid very high doses of nor-epinephrine (>0.3 mcg/kg/min) in the background of severe pulmonary hypertension (systolic pulmonary pressure> 90 mmHg). Its effects such as decreased oxygen demand, positive inotropy and better right ventricle performance probably helped to improve oxygenation in presence of pulmonary oedema.engAdultCardiopulmonary Bypass --adverse effectsHeart Failure --complicationsHumansHypotension --etiologyHypothermia, InducedMaleMitral Valve Stenosis --complicationsPulmonary Edema --etiologyRheumatic Heart Disease --complicationsSyndromeTreatment OutcomeVascular ResistanceVasodilationCase Reports