Anand, N KChellani, H KWadhwa, APrasanna, S BMohan, M1991-02-012009-05-271991-02-012009-05-271991-02-01Anand NK, Chellani HK, Wadhwa A, Prasanna SB, Mohan M. Congenital syphilitic hepatitis. Indian Pediatrics. 1991 Feb; 28(2): 157-9http://imsear.searo.who.int/handle/123456789/7776Hepatitis is a known manifestation of congenital syphilis, however hepatitis developing during penicillin therapy is unknown. Ten patients of congenital syphilis were studied and serial liver enzymes were done before and after starting penicillin therapy. Eight of the ten patients developed hepatitis after initiating penicillin therapy. Whether hepatitis in these cases was secondary to toxic reaction to the products of treponemal lysis or an autoimmune reaction needs to be investigated.engAlanine Transaminase --bloodAspartate Aminotransferases --bloodHepatitis --bloodHumansInfant, NewbornPenicillin G, Procaine --therapeutic useSyphilis, Congenital --complicationsJournal Article