Akbulut, H HDeveci, FCelik, IIlhan, FTurgut, T2009-01-282009-05-282009-01-282009-05-282009-01-28Akbulut HH, Deveci F, Celik I, Ilhan F, Turgut T. Investigation of T cell receptors in the peripheral blood of patients with active pulmonary tuberculosis. Indian Journal of Medical Microbiology. 2009 Jan-Mar; 27(1): 40-3http://imsear.searo.who.int/handle/123456789/53930T cells have the capability of recognizing target cells through their T cell receptors (TCRs). Thus, the percentages of CD3+/gamma-delta (gammadelta) TCR+ and CD3+/alpha-beta (alphabeta) TCR+ T lymphocytes were investigated in active and inactive pulmonary tuberculosis (PT) patients and in healthy individuals. CD3+ and CD3+/alphabeta TCR+ cell percentages were significantly lower in all PT patients than in healthy subjects. Percentages of CD3+/gammadelta and CD3+/alphabeta TCR+ were not statistically different between active and inactive PT patients. It was concluded that alphabeta TCR+ T cells might have a protective role in tuberculosis infection.engAdultAntigens, CD3 --analysisBlood --immunologyFemaleHumansMaleMiddle AgedReceptors, Antigen, T-Cell --immunologyT-Lymphocyte Subsets --immunologyT-Lymphocytes --immunologyTuberculosis, Pulmonary --immunologyYoung AdultJournal Article