Panadda Suwan2011-02-222011-02-222010-01-062010-01-06Vajira Medical Journal; Vol. 53 No. 1 January - April 2009; 89-100http://imsear.searo.who.int/handle/123456789/133092Abstract Use of Intravenous Immunoglobulin (IVIg) Panadda Suwan MD Department of Pediatrics, BMA Medical College and Vajira Hospital           Initially used as a replacement therapy for immunodeficiency diseases, intravenous immunoglobulin (IVIg) is now widely used for a number of autoimmune and inflammatory diseases. The mechanisms of action of IVIg are several, it can modulate an immune reaction at the level of T cells, B cells, macrophages, the complement cascade and the cytokine network. Given the potential risks and cost-effectiveness of IVIg, careful consideration of the indications and administration of IVIg is warranted. Vajira Med J 2009 ; 53 : 89 - 100en-USFaculty of Medicine, Vajira Hospital, University of Bangkok Metropolis, Bangkok, ThailandReview Articles