MAHAJAN, SANYAM KVERMA, BALBIR SSHARMA, SUNILMAHAJAN, KUNALSINGH, BALRAJ2023-06-272023-06-272021-12MAHAJAN SANYAM K, VERMA BALBIR S, SHARMA SUNIL, MAHAJAN KUNAL, SINGH BALRAJ. Prevalence of obstructive sleep apnoea among patients admitted with acute coronary syndrome in a hill state of northern India. The National Medical Journal of India. 2021 Dec; 34(6): 337-3400970-258X2583-150Xhttp://imsear.searo.who.int/handle/123456789/218169BACKGROUND Obstructive sleep apnoea (OSA) is one of the emerging non-traditional cardiovascular risk factors. Studying OSA may contribute towards a better understanding of current concepts of atherogenesis and in guiding therapy. METHODS We conducted this cross-sectional study among 66 patients with acute coronary syndrome (ACS) in a tertiary care hospital from 1 January 2019 to 30 June 2020. We included patients of ST elevation myocardial infarction (STEMI)/ non-STEMI (on achieving Killip class I/II) and unstable angina and performed in-hospital overnight polysomnography (PSG) within 8 weeks of index event. Apnoea–hypoapnoea index (AHI) value 5–<15 was defined as mild OSA, AHI 15–<30 as moderate OSA and AHI >30 as severe OSA. We analysed data using Epi Info version 7.2.4 for Windows. RESULTS The 66 patients had a mean (SD) age of 57.7 (11.1) years and 54 (81.8%) were men. Forty-three (65.1%) patients had STEMI, 19 (28.7%) had non-STEMI and 4 (6%) had unstable angina. On PSG, the prevalence of OSA (AHI>5) was 78.8% (95% CI 67.0–87.9). Of these, AHI >15 was significantly associated with diabetes, hypertension and different measures of obesity (p<0.05). CONCLUSIONS This study, conducted in a hill state of northern India, showed a high prevalence of OSA in patients with ACS. Obesity, diabetes mellitus and hypertension were significantly associated with severity of OSA (AHI>15).Journal ArticleIndiaDepartment of Medicine, Indira Gandhi Medical College, Shimla 171001, Himachal Pradesh, IndiaDepartment of Pulmonary Medicine, Critical Care and Sleep Medicine, Shimla 171001, Himachal Pradesh, IndiaDepartment of Cardiology, Critical Care and Sleep Medicine, Shimla 171001, Himachal Pradesh, IndiaDepartment of Community Medicine, Critical Care and Sleep Medicine, Shimla 171001, Himachal Pradesh, India